摘要
目的:以玉米低营养饲料喂养小鼠为实验动物模型,结合已建立的食品BDI-GS评价新体系对比评价3种市售常见鲜品山药食用的补益及健康效应。方法:以线性生长期的健康ICR小鼠为研究对象,空白对照小鼠喂食单纯玉米饲料,受试物小鼠喂食含20%鲜品普通怀山药、铁棍山药和山药豆的玉米掺和饲料,共喂养12d。隔天称取体重1次,末次称重后眼眶取血、处死解剖,通过统计9项脏器组织重量、系数及其BDI和GS等指标进行评价,并进行血清生化分析测试。结果:山药豆喂养小鼠在促进生长发育方面表现最佳,其综合补益效应(累计GSW)也明显优于铁棍山药及普通怀山药;而综合健康效应略低于铁棍山药。山药豆及铁棍山药对部分脏器指标存在补益和有益健康的效应,主要表现在心脏、胸腺、脾脏、胰腺和肾脏的BDI均高于1.0,部分指标与空白对照比较存在显著性差异(P<0.05及P<0.01)。然而,普通怀山药与空白小鼠脏器指标BDI比较虽有一定差异,但统计学上均无显著性,表明其补益及健康相应相对较低。结论:本研究表明山药豆的补益效应最佳,其次是铁棍山药;铁棍山药的健康效应最佳。二者对Ⅱ型糖尿病均具有一定的食疗预防功效,相关的保健食品值得开发。
Objective: The current study on replenishing and healthy effects of 3 species of marketing Yam Rhizoma( YR) was comparatively evaluated by maize low- nutritional diet for mice model combined novel BDI- GS food evaluation approach. Method: The healthy rodent ICR mice during linear growth were selected in the study. The control mice were fed with common maize low- replenishing diets and the treated mice fed with maize blending diets of 20% common YR,Tiegun YR and YR beans,respectively,for 12 days in total. We weighed body masses once every two days. After masses weighing in the end,we took blood samples by orbital vessels,and the evaluation was performed by absolute and relative masses of 9 organs and / or tissues statistically analyses. Their BDI and GS values calculation and serum biochemical indicators were measured. Results: The growth and development performance of YR beans fed mice showed the best in the current study,and its overall replenishing effects( integrated GSWvalue) was obvious higher than that of Tiegun YR and common YR,but overall healthy effect was slight lower than that of Tiegun YR. The replenishing and healthy indicators of part organ for both YR beans and Tiegun YR fed mice were of beneficial effects,mainly expressions in the BDI values of heart,thymus,spleen,pancreas and kidneys were all above 1. 0,and part indicators were of significant differences by compared with control( P〈0. 05,P〈0. 01). Nevertheless,organ indicators of common YR fed mice were just of a little difference compared with those of control mice,but all not of significances in statistics,demonstrating that its replenishing and healthy effects were relatively lower. Conclusion: The current study manifests that YR beans is of the best replenishing effect. The next is Tiegun YR and its healthy effect is the best. Both types fresh Yam Rhizoma are of better nutritive preventing and treating effects to type 2 diabetic mullitus and related health- promoting foods are worthy of development.
出处
《中华中医药学刊》
CAS
2014年第12期3031-3035,共5页
Chinese Archives of Traditional Chinese Medicine
关键词
BDI-GS体系
普通怀山药
铁棍山药
山药豆
补益与健康
功效评价
BDI-GS system
common Yam Rhizoma
Tiegun Yam Rhizoma
Yam Rhizoma beans
nutrition and health
functional evaluation