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胃镜活检胃癌组织Her-2蛋白表达及意义 被引量:4

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摘要 目的探讨人表皮生长因子受体2(Her-2)在胃镜活检胃癌组织中的表达与胃癌生物学行为的相关关系。方法采用SP免疫组化技术检测567例胃镜活检胃癌组织中Her-2蛋白的表达,并将检测结果与胃癌临床病理特征进行相关性分析。结果 567例胃癌组织中,Her-2蛋白阳性表达率为15.16%(86/567);Her-2蛋白表达与肿瘤分化程度、病理类型有关(P<0.05),但与患者年龄、性别、肿瘤部位无关(P>0.05)。结论 Her-2蛋白表达与胃癌病理特征相关,对胃癌胃镜下活检组织Her-2表达的检测对治疗方式选择有一定指导意义。
出处 《广东医学》 CAS CSCD 北大核心 2014年第22期3552-3554,共3页 Guangdong Medical Journal
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