β-环糊精改性壳聚糖微球的制备及其性能研究

Study on Preparation and Capacities of the Chitosan Microspheres Modified by β-cyclodextrin

采用反相悬浮法,通过环氧氯丙烷交联制备β-环糊精改性交联壳聚糖微球(CDS),用FTIR和SEM进行表征,研究其对甲基橙(MO)的吸附和缓释性能。考察吸附时间、溶液p H值、MO浓度、温度等因素对CDS微球吸附的影响,并与交联壳聚糖(CTS)微球进行比较。结果表明,在p H 4.0、交联CTS微球1h可达吸附平衡,而CDS 2 h达到平衡;吸附数据均符合Freundlich等温方程和二级动力学方程。

The chitosan microspheres immobilized with β-cyclodextrin （CDS）were prepared by reversed-phase suspension,cross linked with epichlorohydin,and the adsorption capacities of the modified micro-spheres for methyl orange （MO）were studied.The structure of microspheres was characterized by FTIR and SEM.The effects of adsorption conditions,such as time,pH,temperature,the concentration of MO and the CDS microspheres adsorption efficiency. The experimental results suggested that, at pH4.0, adsorption balance time of cross-linking chitosan microspheres was 1 h.CDS of microspheres was 2 h.Ad-sorption data were fitted to the Freundlich isothermal equation and second-order kinetic.