犬血清白蛋白-白细胞介素融合蛋白的表达研究
摘要
白细胞介素是动物体中重要的免疫细胞因子之一,其抗病毒、抗肿瘤、调节其他相关免疫程序等作用受到重视,并不断进行改进、开发和利用。目前,人医临床上各种改良的白细胞介素药剂已经陆续投入研发和使用,其中针对白细胞介素可能诱发的不良反应及其半衰期偏短等缺点的研究,是努力改进的主要方向之一。试验拟用常见动物犬血清白蛋白(CSA)与犬白细胞介素-2(IL-2)构建融合蛋白,延长犬白细胞介素的半衰期,进而探讨动物临床长效重组白细胞介素的可行性。
出处
《黑龙江畜牧兽医》
CAS
北大核心
2014年第12期196-198,共3页
Heilongjiang Animal Science And veterinary Medicine
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