西安市2008-2013年其他感染性腹泻流行病学及病毒学病原特征分析

Epidemiologic analysis on other infectious diarrheal diseases in Xi'an city in 2008-2013

目的了解西安市其他感染性腹泻的发病情况和流行特征,以及病毒学病原构成特征,为制定防控策略提供依据。方法用描述流行病学方法对西安市2008-2013年报告的其他感染性腹泻病进行分析。在西安市设立5所哨点医院,采集2008-2010年14岁以上腹泻患者的粪便标本,运用ELISA、PCR和RT-PCR方法对常见致腹泻病毒(杯状病毒、轮状病毒、腺病毒和星状病毒等)进行检测。结果 2008-2013年西安市共报告其他感染性腹泻34 396例,年平均发病率70.15/10万,发病率总体呈上升趋势,2012年最高87.94/10万。年平均死亡率为0.01/10万。西安市成人腹泻的病毒学病原主要以诺如病毒为主。结论西安市其他感染性腹泻发病率仍较高,且逐年上升,应继续做好综合防制工作。

Objective To investigate the epidemiology and virological etiology of other infectious diarrheal diseases in Xi＇ an city for providing the basis for formulating the prevention and control strategies.Methods The reported data of other infectious diarrheal diseases in Xi＇ an city from 2008 to 2013 were analyzed by descriptive epidemiological methods.The stool samples were collected from outpatients （＞ 14 years old） with diarrhea in 5 hospitals in Xi＇ an to detect calicivirus,rotavirus,adenovirus and astrovirus by ELISA,PCR and RT-PCR.Results A total of 34 396 cases of other infectious diarrheal diseases were reported in Xi＇ an city from 2008 to 2013,with an annual incidence of 70.15/100 000.The overall incidence was in an upward trend,with the highest annual incidence of 87.94/100 000 in 2012.Average annual mortality was 0.01/100 000.Adult patients with diarrhea was mainly infected by norovirus in Xi＇ an.Conclusion The prevalence of other infectious diarrheal disease is comparatively high in Xi＇ an,and increases year by year.Thus the prevention and control should be strengthened.