小果蔷薇三萜酸类化学成分的研究

Triterpene constituents from Rosa cymosa Tratt.

采用柱色谱技术对小果蔷薇Rosa cymosa Tratt.根的95%乙醇提取物进行化学成分的研究,从小果蔷薇中分离得到11个化合物,根据波谱数据结合理化性质确定各化合物的结构,分别鉴定为坡模酸（1）,覆盆子酸（2）,乌苏酸（3）,蔷薇酸（4）,阿江榄仁尼酸（5）,委陵菜酸（6）,3β-E-feruloyl corosolic acid（7）,1β-羟基蔷薇酸（8）,千花木酸（9）,2,3-断-19α-羟基-12-稀-乌苏-2,3,28-三羧酸（10）,冬青苷B（11）。化合物3,6~8,10,11为首次从该植物中分离得到,其中化合物7,10为首次从蔷薇属分离得到。

The constituents in 95% ethanol extract of the root of Rosa cymosa Tratt were purified by column chromatography techniques, leading to isolation of eleven triterpenes. Their structures were elucidated by spectroscopic data as pomolie acid （ 1 ）, fupenzic acid （2）, ursolic acid （3）, euseaphic acid （4）, arjunic acid （5）, tomentie acid （6）, 3β-E-feruloyl corosolic acid （7）, 1β- hydroxyeuscaphic acid （8） , myrianthic acid （9） , cecropiacie acid （10） , and ilexoside B （11）. Among them, compounds 3, 6-8, 10 and 11 were obtained from this plant for the first time, and compounds 7 and 10 were obtained from this genus for the first time.