弹性成像技术在眼部良恶性肿瘤鉴别诊断中的应用价值

Application value of ultrasonic elastography to identify benign and malignant ocular tumor

目的探讨实时组织弹性成像技术对眼部肿瘤良恶性病变鉴别诊断中的应用价值。方法对68例眼部肿瘤患者行彩色多普勒超声和实时组织弹性成像检查，获得相应的弹性图像并进行弹性评分，以手术病理结果为诊断金标准，对比分析实时组织弹性成像与彩色多普勒超声诊断眼部肿瘤良恶性的准确性。结果眼部良恶性肿瘤中彩色多普勒血流分级、弹性成像评分差异均有统计学意义（P〈0．05），以弹性评分≥4分为高度恶性预测指标，其诊断眼部恶性肿瘤的敏感性、特异性、准确性分别为85．7％、90．0％、88．2％，结合彩色多普勒诊断眼部良恶性肿瘤的敏感性、特异性、准确性显著提高。结论弹性成像在眼部肿瘤的定性诊断中具有较高的应用价值，而与彩色多普勒相结合可以提高眼部肿瘤鉴别诊断的准确性。

Objective To investigate value of real-time tissue ultrasonic elastography （UE） to the differential diagnosis of benign and malignant ocular tumor. Methods 68 ocular tumor patients were examined with color Doppler flow imaging （CDFI）and real-time UE respectively. The elastography and elastic scores were obtained, and were compared with the histopathological results as the diagnosis golden standard to evaluate the accuracy of elastic scores and CDFI classification in the diagnostic of benign and malignant ocular tumor. Results There was a significant difference between benign and malignant ocular tumor of CDFI and elastic scores （ P 〈0.05）.Taking the elastic scores ≥4 as the standard for diagnosing malignant ocular tumor, the sensitivity, specificity and accuracy of the elastic scores were 85.7%, 90.0%, 88.2% for malignant ocular tumor. Conclusions UE has the higher qualitation diagnosis value to ocular tumor,combined with CDFI could improve the diagnosing accuracy in ocular benign and malignant tumor.