LEEP刀治疗宫颈上皮内瘤变临床疗效观察

Clinical observation of LEEP knife treatment of cervical intraepithelial neoplasia

目的探讨LEEP刀治疗宫颈上皮内瘤变(CIN)的临床疗效。方法将2008年11月至2013年3月在我院妇产科就诊的309例CIN患者分为两组,其中观察组179例采用环行电切术(LEEP刀)治疗、对照组130例采用冷刀锥切术治疗,观察比较两组患者的术中情况及临床疗效。结果观察组患者的平均手术时间、术中出血量、愈合时间、住院时间及总住院费用等均明显低于对照组,差异有统计学意义(P<0.05);两组患者的临床效果及术后并发症发生率比较,差异无统计学意义(P>0.05)。结论 LEEP刀是一种治疗CIN的安全、有效方法,值得在临床上推广应用。

Objective Study on the clinical efficacy of LEEP knife treatment of cervical intraepithelial neoplasia（CIN）.Methods From November 2008 to March 2013,treated in hospital of Gynecology and obstetrics,309 cases of CIN were divided into two groups,179 in the observation group were treated with Loop Electrosurgical Excision Procedure（LEEP knife）in the treatment,control group of 130 cases with cold knife conization treatment,observe all patients during operation and clinical curative effect.Results Observe group average operating time、Intraoperative bleeding、union time、hospitalization time and total hospital costs are significantly lower than control group,there was a statistically significant difference（P〈0.05）;The clinical effect of two groups of patients and postoperative complication rate compared,no significant difference（P〉0.05）.Conclusion LEEP knife is a safe and effective method of treatment of CIN,deserve used in clinical practice.