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ACE2-Ang(1-7)-Mas轴的生物学功能及其下游信号通路 被引量：16

The biological functions of ACE2-Ang( 1-7)-Mas axis and its downstream signaling pathways
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摘要 ACE2-Ang(1-7)-Mas轴具有拮抗ACE-AngⅡ-AT1R经典轴的作用,参与体内众多的生理反应。在循环、泌尿和消化等系统及炎性反应中发挥着重要的保护作用。ACE2-Ang(1-7)-Mas轴功能的发挥与其信号通路密切相关。探讨此调节轴的生物学功能及其信号传导通路将为相关疾病的治疗提供新的思路。 ACE2-Ang（ 1-7 ）-Mas axis antagonistics ACE-Ang Ⅱ-AT1R classic axis in many physiological responses, which plays an important protective role in circulation, urinary, digestive systems and inflammation response. The biological function of ACE2-Ang（ 1-7 ） -Mas axis is closely related to its signaling pathways. Exploring the biological function of this adjustment axis and its signaling transduction pathways will provide new ideas for related diseases.
作者 崔立建 刘瑞霞 王艳 阴赪宏
机构地区 首都医科大学附属北京友谊医院感染内科
出处 《基础医学与临床》 CSCD 北大核心 2014年第12期1718-1722,共5页 Basic and Clinical Medicine
基金 北京市博士后科研活动经费(201322-24)
关键词 ACE2-Ang(1-7)-Mas轴 生物学功能 信号通路 ACE2-Ang（ 1-7 ） -Mas axis biological function signal pathway
分类号 R346 [医药卫生—基础医学]
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参考文献23

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基础医学与临床
2014年 第12期

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