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地佐辛治疗剖宫产患者术中寒战反应的效果 被引量:8

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摘要 目的观察静注地佐辛对剖宫产手术患者椎管内麻醉后寒战反应的治疗效果。方法择期剖宫产术中发生寒战的产妇150例,于胎儿娩出后随机分别静注地佐辛0.15mg/kg(DZ组)、哌替啶1mg/kg(ME组)和生理盐水(C组)治疗。评估用药后寒战反应的改善程度,记录HR、MAP和SpO2的变化,观察患者的不良反应。结果 DZ组和ME组治疗寒战效果优于C组(P<0.05);DZ组和ME组寒战反应的改善率分别为92%和90%(P>0.05)。与用药前比较,用药后5和10min,DZ组和C组的MAP、HR和SpO2均无明显变化,但ME组的MAP降低,HR增快,SpO2降低(P<0.05)。ME组呼吸抑制发生率为2%、恶心呕吐发生率为20%、低氧血症发生率为8%。DZ组无呼吸抑制病例;恶心呕吐发生率为10%、低氧血症发生率2%,均低于ME组(P<0.05)。结论静注地佐辛0.15mg/kg对剖宫产手术患者椎管内麻醉后寒战反应的治疗效果与哌替啶1mg/kg相当,但不良反应少,更适用于剖宫产术中寒战反应的治疗。
作者 聂鑫
出处 《江苏医药》 CAS 北大核心 2014年第22期2779-2780,共2页 Jiangsu Medical Journal
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参考文献4

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