上海市闵行区2002-2012年大肠癌生存趋势分析

Survival trend of colorectal cancer in Minhang District,Shanghai from 2002 to 2012

目的分析2002—2012年上海市闵行区大肠癌患者的生存趋势，为大肠癌的防治研究提供科学依据。方法根据2002—01-01—2012-12-31上海市闵行区肿瘤登记处积累的上海市闵行区大肠癌发病和死亡资料，统计和分析大肠癌年死亡率，1、3和5年生存率等指标。结果上海市闵行区2002—2012年新发大肠癌病例数共为4845例，死亡病例数为2139例，大肠癌每年新发发病例数为323～539例，每年因大肠癌死亡病例数为173～234例。2002年和2012年标化年死亡率为13．71／10万和4．35／10万，P=0．0017；1年生存率由2002年的70％，提高到2012年的81％，P=0．004；3年生存率2002年为61％，2010年仍为61％，P=0．78；5年生存率2002年为57％，2008年为52％，P=0．97。结论2002—2012年上海市闽行区大肠癌患者1年生存率显著提高，但长期生存率改善不明显。应着力加强防治研究．

OBJECTIVE To analyze the incidence and mortality of colorectal cancer in Minhang district, Shanghai from 2002 to 2012 to provide a epidemiological profile for further research. METHODS The data of co[orectal cancer ca- ses in Minhang district, Shanghai were collected by the Minhang,Shanghai Cancer Registry from January 1,2002 to De- cember 31, 2012. The rates of mortality and survival periods for colorectal cancer were presented. RESULTS There were 4 845 cases reported,and 2 139 cases dead. There were 323--539 colorectal cancer cases reported, and 173--234 ca- ses died. The age-standardized annual mortality rates of colorectal cancer from 2002 to 2012 were between 13.71/10^5 and 4.35/10^5 , with statistically significant difference（P=0. 001 7）. During this period, one-year survival rate, three-year sur- vival rate and five-year survival rate were 70% vs 81%（P=0. 078）,61% vs 61%（P=0. 004）,57% vs 52%（P=0.97）re- spectively. CONCLUSIONS Colorectal cancer is one of the most common cancer in Minhang District Shangha,although short-term survival rate is improved significantly, the long-term survival rate is not changed during the past ten years. Prevention and control for colorectal cancer should be strengthened.