口腔癌下颌骨侵犯途径及方式的研究进展

Advances in the patterns and pathways of bone invasion by oral cancers

口腔癌常易侵犯下颌骨,且下颌骨的侵犯对其治疗及预后中十分重要。作为一个重要的功能器官,下颌骨的保存在口腔癌的治疗过程中受到越来越多医师的关注。然而,当口腔癌侵犯下颌骨后,是否应该保存及通过何种方式保存下颌骨尚存在争议。而这些争议的根源来源于目前对于口腔癌侵犯下颌骨的途径及方式不明确。本文将对口腔癌下颌骨侵犯的途径及方式的研究进展进行综述。

Oral cancer grows invasively and is a common malignancy that invades bone tissues. Mandibular involvement is a key aspect in the treatment and prognosis of oral cancer. The preservation of the mandible, an important functional organ, has attracted increasing attention. However, the procedures for mandible preservation and mandibulectomy are inconsistent among oral and maxillofacial surgeons. The discrepancies are primarily caused by the uncertainty of the exact patterns of bone invasion by oral cancers. This article reviews the present materials to explore the mechanisms involved in mandibular preservation and mandibulectomy in oral cancer treatment.