应用Tei指数评价正常和宫内缺氧胎儿心功能

Using Tei index for evaluating cardiac function in normal fetuses and fetuses with intrauterine hypoxia

目的 探讨Tei指数（心脏做功指数）在评价正常胎儿和宫内缺氧胎儿心功能中的应用价值.方法 分别测量300例正常胎儿（300例按孕龄分组：20～25＋6周,26～30＋6周,31～35＋6周,36～40周,每组75例）和25例宫内缺氧胎儿的Tei指数,分析两者之间差异有无统计学意义.结果 300例正常胎儿左心室Tei指数为0.30±0.09,右心室Tei指数为0.34±0.07,右心室Tei指数略高于左心室Tei指数,两者之间具有相关性（r=0.272,P＜ 0.01）.正常组不同孕龄、不同心率胎儿之间的左、右心室Tei指数分别进行比较,差异均无统计学意义（P＞0.05）.25例宫内缺氧的胎儿左心室Tei指数为0.21±0.09,右心室Tei指数为0.25±0.13,比正常胎儿左、右心室Tei指数明显减低,差异有统计学意义（P＜0.01）.结论 对比正常组胎儿,宫内缺氧组胎儿Tei指数减低,差异有统计学意义.提示Tei指数可作为宫内缺氧胎儿的心功能监测指标.

Objective To explore the use of Tei index （myocardial performance index） for evaluating cardiac function in normal fetuses and fetuses with intrauterine hypoxia.Methods Three hundred normal fetuses （stratified by gestational age：20 to 25＋6 weeks,26 to 30＋6 weeks,31 to 35＋6weeks,36 to 40 weeks,n=75 in each level） and 25 fetuses with intrauterine hypoxia were measured for Tei index.Statistical analysis was performed to test the difference of Tei index between two groups.Results Among 300 normal fetuses,the Tei index was 0.30±0.09 for the left ventricle,which was slightly greater than the 0.34±0.07 for the right ventricle.There was a correlation between Tei indexes of two ventricles （r =0.272,P ＜ 0.01）.Tei index of left or right ventricle did not differ statistically with gestational ages and fetal heart rates （P ＞ 0.05）.Among 25 fetuses with intrauterine hypoxia,the Tei index was 0.21±0.09 for the left ventricle and 0.25±0.13 for the right ventricle,both significantly lower than those in normal fetuses （P ＜ 0.01）.Conclusion Compared with normal fetuses,fetuses with intrauterine hypoxia show significantly reduced Tei index,suggesting that Tei index may be used as a parameter for monitoring cardiac function in fetuses with intrauterine hypoxia.