老年重症肺炎患者血清降钙素原检测的临床价值

The detection of serum procalciton in level in the elderly with severe pneumonia and the clinical significance

目的:探讨老年重症肺炎患者血清降钙素原检测的临床价值。方法:收集40例重症肺部感染患者(重症组)、40例非重症肺部感染患者(非重症组)、40例体检健康者(健康组),分别测定各组血清降钙素原、超敏C反应蛋白、白细胞计数及体温,并进行比较分析。结果:重症组的血清降钙素原浓度(5.69±7.38)ng/mL与非重症组(0.76±0.65)ng/mL及健康组(0.13±0.12)ng/mL比较差异均有统计学意义(P<0.05);而重症组的超敏C反应蛋白、白细胞计数及体温与非重症组比较差异均无统计学意义(P>0.05)。结论:血清降钙素原与老年肺部感染的严重程度密切相关,血清降钙素原可作为判断病情的指标。血清降钙素原可较好地预测老年重症肺炎患者的预后。

Objective： To investigate the value of serum procalcitonin （ PCT） determination for risk evaluation in elderly patients with severe pneumonia. Methods： The levels of serum PCT, high sensitive C-reactive protein （hsCRP）, white blood cell count and temperature were measured in 40 patients with severe pneumonia （severe group）, 40 cases of mild to moderate pneumonia （non-severe group） and 40 normal healthy persons （healthy group） .The differences of the levels of them among the groups were compared. Results：The serum PCT level was （5.69±7.38）ng/ mL in severe pneumonia patients, which was significantly higher than that in mild to moderate pneumonia patients （0.76±0.65）ng/ mL and healthy persons（0.13±0.12）ng/ mL （P〈0.05）, but there was no difference between severe group and non-severe group in the levels of hsCRP and WBC （P〉0. 05） . Conclusions：Serum PCT levels correlated with severitvy and it can be useful for assessment of the severity of severe pneumonia in elderly patients. PCT levels can predict prognosis better in elderly patients with severe pneumonia.