CRP在微创手术及传统手术前后变化的临床意义

Clinical significance of CRP in minimally invasive surgery and traditional operation

目的探讨C反应蛋白(CRP)在传统手术与微创手术前后的变化及其与机体感染、创伤的相关意义。方法将146例研究对象分为微创组(n=79)和传统组(n=67),检测两组术前、术后CRP的含量和白细胞数(WBC)以及中性粒细胞百分比(N%)。结果微创组和传统组术后CRP、WBC、N%均高于术前,差异有统计学意义(P<0.05)。传统组术后CRP结果高于微创组,差异有统计学意义(P<0.05)。微创组术前WBC结果低于传统组,差异有统计学意义(P<0.05)。微创组术前CRP与WBC、N%结果相关且有统计学意义(P<0.05),而术后结果不相关。结论 CRP检测对评估手术创伤、应激或炎症反应具有重要的临床应用价值。

Objective To investigate the CRP changes before and after traditional operation and minimally invasive surgery,and its relationship with infection and traumaor. Methods The research subjects were divided into minimally invasive surgery group and traditional operation group. CRP, WBC and N% in all subjects before and after operation were measured.Results The results of CRP, WBC and N% in post-operation subjects were apparently higher than those in the pre-operation subjects in the two groups; the differences had statistical significance（P〈0.05）. The results of CRP in the traditional postoperation were higher than those in the minimally invasive surgery post-operation group; differences had statistical significance（P〈0.05）. The results of WBC in the minimally invasive pre-operation surgery group were lower than those in the traditional pre-operation group; differences had statistical significance（P〈0.05）. The result of CRP was correlated with the WBC and N%in the minimally invasive surgery pre-operation group; differences had statistical significance（P〈0.05）. Conclusion Detection of CRP had clinical significant in evaluation of operation trauma, stress and inflammation.