慢性非萎缩性胃炎与幽门螺杆菌感染的相关性分析

Correlation between chronic non-atrophic gastritis and helicobacter pylori infection

目的探讨慢性非萎缩性胃炎的胃黏膜炎症的程度、部位、活动性与幽门螺杆菌(Helicobacter pylori,Hp)感染的关系,为临床胃炎抗Hp治疗提供理论依据。方法对胃镜诊断为慢性非萎缩性胃炎的165例患者行活检病理诊断及Hp检测,然后对资料进行分析整理。结果 165例慢性非萎缩性胃患者Hp感染率为41.82%,与性别、胃黏膜炎症的程度、活动性均呈显著正相关(P<0.01),但与年龄、炎症部位差异均无统计学意义(P>0.05)。结论 Hp感染与慢性非萎缩性胃炎的程度、活动性有关,慢性非萎缩性胃炎有必要作抗Hp根除治疗。

Objective To provide theoretical evidence for anti- Helicobacter pylori （Hp）infection in gas-tritis treatment by finding correlation between Hp and the severity,location and activity of gastric mucosa in-flammation in chronic non-atrophic gastritis. Methods Pathological biopsy diagnosis and Hp detection in 1 65 patients with chronic non-atrophic gastritis proven by gastroscopy were performed,and then the collected data were analyzed. Results In 1 65 specimens of non-atrophic gastritis,41.82% of them got positive-Hp infection.These data showed that Hp infection had significantly positive association with gender,severity and activity of the chronic non-atrophic gastritis（P〈0.01）,but had not significant differences with age and in-flammatory location （P〉0.05）. Conclusion This study suggested that Hp infection has correlation with severity and activity of chronic non-atrophic gastritis,and it is necessary for Hp eradication therapy in chronic non-atrophic gastritis.