摘要
目的:探讨18F-FDG符合线路SPECT/CT显像在肺癌诊断和淋巴转移探查中的价值。材料与方法:57例疑似肺癌患者进行18F-FDG符合线路SPECT/CT显像,以术后病理结果作为金标准,判断18F-FDG符合线路SPECT/CT显像诊断肺癌的灵敏度、特异性、假阴性率、假阳性率及符合率。结果:57例患者中,符合线路SPECT/CT显像诊断肺癌的灵敏度为95.92%(47/49),特异性为75%(6/8),假阳性率为25%(2/8),假阴性率为4.08%(2/49)及符合率92.98%(53/57)。47例真阳性病例中,18F-FDG符合线路SPECT/CT显像提示淋巴结及其他脏器转移者为82.98%(39/47)。结论:符合线路SPECT/CT显像对肺癌定性诊断的灵敏度高,特异性好,对淋巴结转移及其他脏器转移灶的探查有很好的价值,可为确定临床分期、制定治疗方案及判断预后提供有益的参考。
Purpose: To explore the value of ^18F-FDG Coincidence SPECT/CT in diagnosis of lung cancer and evaluate lymph node metastasis. Materials and Methods: 57 cases of suspected lung carcinoma patients were examined by ^18F-FDG Coincidence SPECT/CT; the results were compared with the pathology results. The sensitivity, specificity, false positive rate, false negative rate and accuracy were calculated and analyzed. Results: Compared with pathology resuhs, the sensitivity, specificity, false positive rate, false negative rate and accuracy of ^18F-FDG Coincidence SPECT/CT detection for lung cancer were 95.92%, 75%, 25% , 4. 08% and 92. 98%, respectively. To 47 lung cancer patients, 82. 98% patients were found the metastasis of lymph node or other viscera in 18 F-FDG coincidence SPECT with 2. 5 mA X-ray device imaging. Conclusion:^18F-FDG Coincidence SPECT with 2. 5 mA X-ray device imaging has a perfect specificity and sensitivity in diagnosis of lung cancer and the lymph node or other viscera metastasis. It will play an important role in clinical staging, therapeutic strategy selection, and prognosis evaluation of lung neoplasm.
出处
《现代医用影像学》
2014年第5期525-527,548,共4页
Modern Medical Imageology