原发性肝癌行TACE术后对乙型肝炎病毒影响

The influence of TACE for primary hepatocellular carcinoma on hepatitis B virus

原发性肝癌是我国常见的恶性肿瘤之一,具有早期症状不明显、发展速度快、预后差等特点。患者有临床症状时大多已属中、晚期,临床中,经导管动脉化疗栓塞术(TACE)是对失去手术机会的中晚期肝癌患者的首选方法之一。对乙型肝炎病毒(HBV)感染相关的原发性肝癌患者,TACE术是否能引起HBV激活,国内外学者对此的相关报道并未统一,本文就乙型肝炎相关性肝癌TACE术后对HBV激活影响的研究作一综述。

Primary hepatocellular carcinoma （HCC） has been one of the most common malignant tumors in China. At its early stage HCC shows no obvious clinical symptoms or signs, nevertheless, the disease is rapidly progressive usually with a poor prognosis. In most cases, the disease is fairly far advanced once the patient develops symptoms. Clinically, transcatheter arterial chemoembolization （TACE） has been one of the treatments of first choice for patients with advanced HCC who have lost the opportunity of radical surgery. The occurrence of HCC is somewhat related to the infection of hepatitis B virus （HBV）. With respect to whether or not HBV can be reactivated after TACE, the research workers, both at home and abroad, have different point of views. This paper aims to make a brief review about the influence of TACE on the reactivation of HBV in patients with HBV-related HCC. （J Intervent Radiol, 2014, 23：1114-1116）