摘要
2014年2月,死亡率极高的埃博拉病(EVD)开始在西部非洲的几内亚暴发流行,接下来,暴发流行出现在塞拉利昂、利比里亚、尼日利亚和塞内加尔另四个西部非洲的国家。现在,几内亚、利比里亚和塞拉利昂的疫情最重。迄今为止,已有4 784人患EVD,且人数仍在倍增,这次暴发流行已成为自40年前EVD被发现以来规模最大的一次,已形成了波及其他地区和国家的巨大危险。在此,综述2014年EVD暴发流行的起因,埃博拉病毒(EBOV)及其传播,EVD的诊断治疗,EBOV疫苗的研制以及EBOV感染的防控。
In February 2014, a devastating Ebola outbroke started in Guinea and then spread into Liberia, Sierra Leone, Nigeria and Senegal in West Africa. Now, Guinea, Liberia, and Sierra Leone are the worst-affected states. The outbroke has killed more than 4 784 people and begun to grow exponentially, making this the most deadly assault of Ebola on human ever since the disease was identified 40 years ago. This fast pace of the outbroke raises the danger of increasing local and international dissemination of the deadly disease. Here, I review recent advances in the understanding of the outbroke, Ebo- la virus and its transmission, Ebola virus disease and its diagnosis/treatment, vaccine development as well as the way to get this epidemic under control.
出处
《微生物学免疫学进展》
2014年第6期1-7,共7页
Progress In Microbiology and Immunology
关键词
埃博拉病毒
传播
埃博拉病
感染
诊断
治疗
疫苗
防控
Ebola virus （EBOV）
Transmission
Ebola
Infection
Diagnosis
Treatment
Vaccine
Control
