阻塞性睡眠呼吸暂停综合征与神经系统疾病的关系

Relationship of obstructive sleep apnea syndromewithnervous system diseases

阻塞性睡眠呼吸暂停综合征（OSAS）是一种常见的以间断性低氧、觉醒为特征的呼吸和睡眠紊乱，由呼吸道结构性或神经源性病变导致上呼吸道阻塞而引起，与神经系统疾病息息相关。本文主要探讨OSAS与神经系统疾病，如脑卒中、特发性颅内高压症、癫痫、认知功能障碍、前庭系统功能紊乱、脑静脉血栓形成、自主神经功能紊乱、抑郁焦虑、疼痛、白质病变的关系，以提高我国神经科临床医师对OSAS的重视。

Obstructive sleep apnea syndrome（OSAS） refers toa commonbreathing and sleep disorderduring sleep characterized by consequent decreases in oxygen saturation and arousals from sleep, withrepetitive episodes of either complete （apnea） or partial （hypopnea） obstruction of the upper airway caused by structural abnormality of upper airway ornervous system disease, and is closely correlated tonervous system diseases. This article summarized the associations of OSAS with manynervous system diseases, including stroke,idiopathic intracranial hypertension, seizure, cognitive disorder, vestibular system dysfunction, cerebral venous thrombosis, autonomic nerve dysfunction, depression-anxiety, pain and cerebral white matter diseases, so asto arousethe clinical neurologists to concern andpayattention toOSAS.