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术后认知功能障碍与麻醉相关性的研究进展 被引量:7

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摘要 目的:分析麻醉与术后认知功能障碍的相关性。方法:通过对认知功能损害(POCD)的发病情况、危险因素、麻醉与POCD相关性以及麻醉引起POCD的可能机制进行研究,全面分析导致术后认知功能障碍的具体因素,对今后麻醉实施提供可靠依据。结果:POCD发病率较高,与多种因素相关,其中麻醉是导致POCD产生的重要原因,主要包括麻醉方式、麻醉药物两方面;麻醉导致术后认知功能障碍的可能机制是麻醉导致患者发生中枢性炎症、中枢胆碱能系统功能异常、影响体内钙平衡。结论:麻醉是导致POCD产生的重要因素,应尽量避免手术和麻醉,应围绕转归规律、病理生理机制寻找出有效的防治方法,以实现对POCD早发现、早干预、早治疗,进而以完善的早期干预方法保证患者的身心健康。
作者 向玲 孙广运
出处 《中国民族民间医药》 2014年第23期21-23,共3页 Chinese Journal of Ethnomedicine and Ethnopharmacy
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参考文献26

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