心房颤动抗凝治疗进展

Progress of Anticoagulant Treatment in Atrial Fibrillation

心房颤动是最常见的心律失常之一,心房颤动患者脑卒中发生风险显著增高,且较其他原因所致的脑卒中有更高的致残率与病死率,故预防脑卒中是心房颤动治疗的重要环节,抗凝治疗在心房颤动患者管理中的地位及重要性逐渐提高。近年来,在心房颤动抗凝治疗方面有重要进展,现对心房颤动患者脑卒中与出血风险评估、抗凝策略选择及抗凝药物研究最新进展进行综述。

Atrial fibrillation （AF） is one of the most common arrhythmias. AF leads to a significantly increased risk of stroke, and in patients with AF it leads to a higher morbidity and mortality when stroke occurs. Therefore stroke prevention is important in AF patients. In recent years, the research in AF anticoagulant treatment includes risk assessment of stroke and bleeding, anticoagulant strategy selection and novel oral anticoagulant. This article reviews the current progress in treatment of AF in relation to stroke prevention.