肥厚型心肌病的特殊亚型——合并左心室心尖部室壁瘤

A Subgroup of Patients with Hypertrophic Cardiomyopathy Characterized by Left Ventricular Apical Aneurysms

肥厚型心肌病合并有左心室心尖部室壁瘤发生率虽然较低,但是一类未得到充分认识的临床亚型,其合并较高的心血管事件发生率和猝死率,及时识别这类患者并启动抗凝、抗心力衰竭及心律转复除颤器植入可改善临床预后。

Left ventricular apical aneurysms are an uncommon variant of hypertrophic cardiomyopathy. Apical aneurysms in hyper- trophic cardiomyopathy patients are commonly associated with adverse clinical outcomes and sudden death events. Therefore, timely recogni- tion of hypertrophic cardiomyopathy patients with apical aneurysms may alter clinical practice. Timely recognition may involve the use of an implantable cardioverter defibrillator and possibly prophylactic auticoagulation with warfarin in selected patients with larger anenrysms.