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围手术期多模式复合镇痛对膝关节置换患者血流变及粘附因子水平的影响 被引量:2

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摘要 目的探讨围手术期多模式复合镇痛对膝关节置换患者血流变及粘附因子水平的影响。方法选择接受膝关节置换的患者81例,随机分为对照组及观察组,对照组仅接受常规硬膜外麻醉,观察组在此基础上接受多模式复合镇痛,观察深静脉血栓(DVT)及术前、术后的视觉模拟评分(VAS)、血流变指标、细胞间黏附分子-1(ICAM-1)、血管细胞粘附因子-1(VCAM-1)的变化。结果观察组接受多模式复合镇痛后DVT发生6例,观察组3例,观察组DVT发生率低于对照组(P<0.05);术后1、3、5、7d观察组VAS评分均较对照组同期低(P<0.05);对照组术后高切粘度、低切粘度、血小板聚集指数、血浆比粘度比观察组高(P<0.05);观察组与术前比较无变化(P>0.05);对照组术后ICAM-1、VCAM-1水平比观察组高(P<0.05)。结论围手术期多模式复合镇痛有助于缓解膝关节置换患者术后疼痛和改善血流变及粘附因子水平。
作者 李永明 吕涛
出处 《宁夏医科大学学报》 2014年第8期901-903,共3页 Journal of Ningxia Medical University
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