自制坐浴器联合高渗盐水甲硝唑坐浴防治肛周感染

Prevention and treatment of perianal infection by sitz bath with hypertonic saline and metronidazole using a homemade sitz device

目的探讨自制恒温坐浴器联合坐浴液预防急性白血病化疗后肛周感染的临床效果。方法将100例急性白血病化疗患者随机分为对照组和观察组各50例;对照组采用高锰酸钾联合坐浴盆方法;观察组采用自制恒温坐浴器联合高渗盐水加甲硝唑溶液治疗。结果观察组治疗20d后肛周状况优于对照组;观察组已感染患者治疗20d后效果显著优于对照组已感染患者(P<0.05)。结论自制恒温坐浴器联合甲硝唑高渗盐水治疗急性白血病患者化疗后肛周感染优于传统的高锰酸钾联合坐浴盆治疗。

Objective To explore the effects of sitz bath using a homemade constant temperature sitz device on preventing perianal infection during chemotherapy for acute leukemia.Methods One hundred patients with acute leukemia receiving chemotherapy were randomly and equally divided into an observation group and a control group.Patients in the control group used traditional sitz baths with potassium permanganate,while their counterparts in the observation group were given sitz baths with hypertonic saline and metronidazole by using a homemade constant temperature sitz device.Results The incidence of perianal infection in the observation group was lower than the control group after 20 d.The therapeutic effect in patients developed perianal infection in the observation group was significantly better than the control group after 20 d （P＜0.05）.Conclusion Sitz bath with hypertonic saline and metronidazole using a homemade constant temperature sitz device is more effective than the conventional sitz bath with potassium per manganate on treatment of perianal infection induced by chemotherapy for acute leukemia.