北京市密云县轮状病毒和杯状病毒腹泻流行特征分析

Epideiological Feature of Diarrhea Virus in Miyun County,Beij ing

目的：了解北京市密云县轮状病毒和杯状病毒流行特征。为腹泻防控提供理论依据。方法2011年4月-2014年3月期间，收集密云县三家医院腹泻患者的粪便标本共720例。用 ELISA方法检测轮状病毒（rotavirus，RV），用 RT-PCR方法检测人杯状病毒（humancaliciviruses，HcCV）。结果720例粪便标本中轮状病毒阳性占10.3％（74/720），人杯状病毒阳性占8.8％（63/720）。轮状病毒0-5岁组阳性率最高为19.0％（11/58），而人杯状病毒19-40岁组阳性率最高为23.9％（11/46）。轮状病毒男性患者多于女性，两组差异有统计学意义（P＜0.05）。结论北京市密云县人杯状病毒主要感染人群为男性中青年，秋季多发。轮状病毒主要感染婴幼儿。

Objective To understand the epidemiological feature of rotavirus and humancaliciviruses in Miyun county of Bei-jing and provide theoretical basis for prevention and control.Methods Stool specimens were collected from 240 diarrhea pa-tients in 3 hospitals from April 2011 to March 2012.Enzyme linked immunosorbent assay （ELISA）and reverse transcrip-tion-polymerase chain reaction （RT-PCR）were used to detect rotavirus and humancaliciviruses respectively.Data was statis-tically analyzed.Results The positive rate of rotavirus was present in 10.3%.Positive cases mainly fell in age group 0-5. More male diarrhea patients than female were infected by humancaliciviruses （P〈0.05）.The positive rate of humancalicivir-uses was present 8.8%.Positive cases mainly fell in age group 19-40.Conclusion The humancaliciviruses susceptible pop-ulations were middle-aged youth and male in Miyun,the infection peak of humancaliciviruses is in autumn.The main infection of rotavirus population was babies.