儿童皮肤软组织感染金黄色葡萄球菌的耐药性分析

Analysis on drug resistance of Staphylococcus aureus in skin and soft tissue infections in children

目的观察和分析儿童皮肤软组织感染金黄色葡萄球菌的耐药性,为临床用药提供参考依据。方法收集医院2011年1月-2012年1月180例皮肤软组织感染患儿临床资料,对其送检标本进行分离培养和药敏试验,所得数据采用SPSS17.0软件进行统计分析。结果所有标本分离出121株金黄色葡萄球菌,分离率为67.22%;分离出的金黄色葡萄球菌对红霉素、青霉素、克林霉素的耐药率最高,分别为98.35%、93.39%、91.73%,万古霉素的耐药率最低,为0。结论金黄色葡萄球菌是儿童皮肤软组织感染的主要因素,且金黄色葡萄球菌对克林霉素、红霉素及青霉素等耐药率高,可以作为临床治疗的参考依据。

OBJECTIVE To observe and analyze the drug resistance of Staphylococcus aureus in skin and soft tissue infections in children so as to provide reference for improvement of clinical medication .METHODS Strain speci‐mens from 180 children with skin and soft tissue infections from Jan .2011 to Jan .2012 were collected as research subjects for isolation ,culture and sensitivity test .The obtained results were analyzed with the software SPSS 17 .0 .RESULTS From all the specimens 121 strains of S .aureus were isolated ,the isolation rate was 67 .22% . The isolated S . aureus had the highest resistance rates to erythromycin （98 .35% ） ,penicillin （93 .39% ） ,and clindamycin （91 .73% ） ,and the lowest rate to vancomycin （0） .CONCLUSION S . aureus is a major factor for children′s skin and soft tissue infections ,and the high resistant rate of S . aureus to clindamycin ,erythromycin and penicillin can serve as a reference for clinical treatment .