昆虫感受气味物质的分子机制

Molecular Mechanisms of Insect Accepted Odorant

在昆虫触角中,位于嗅觉感器神经树突膜上的气味受体蛋白与同源配位体相互作用将化学信号转换为神经活动。在与气味受体相互作用前,这些疏水性的配位体必须进入和穿过含有高度聚集气味降解酶的水环境,气味分子和气味结合蛋白OBP相互作用,在水腔和感器的表皮毛壁的交界面上与气味分子结合,通过扩散穿过水腔,将气味运送到神经细胞膜受体。接收后传入中枢神经系统。中枢神经系统对所有感官器官接收信号进行整合,最后使效应器官产生行为反应。对昆虫感受气味物质的分子机制进行了探讨。

Sensors located in the olfactory nerve dendrites odorant receptor membrane proteins interact with cognate ligand chemical signals into neural activity in insect antennae.Before odorant receptor interaction,these hydrophobic ligand must enter and pass through the water environment containing highly aggregated smell degrading enzymes,odor and odor molecules OBP-binding protein interaction,in the water chamber and the sensor trichomes odor molecules at the interface with the wall of the binding,by diffusion through the water chamber,will be transported to the nerve cell membrane receptors odor.After receiving the incoming central nervous system,the sensory organs of the central nervous system integrated all the received signal,and finally made the organ to produce behavioral responses.The molecular mechanisms of insect accepted odorant was discussed.