深圳市疑似寄生虫病例血清抗体检测结果分析

Analysis of detection of serum antibodies in suspected cases with parasitic dseases in Shenzhen city

目的利用疾控检测平台检测寄生虫感染疑似病例血清抗体,为医院诊疗寄生虫病提供技术依据。方法采用寄生虫病诊断标准的ELISA方法,对深圳市、区属医院送检的华支睾吸虫、日本血吸虫、广州管圆线虫及棘球蚴病疑似病例血样进行血清抗体Ig G检测。结果深圳市、区属医院896份寄生虫病疑似病例血清样本4种寄生虫抗体总阳性率为14.1%(126/896),其中深圳市、区属医院血样抗体阳性率分别为13.6%(100/734)、16.0%(26/162),抗体阳性率间的差异无统计学意义(χ2=0.646,P>0.05);华支睾吸虫、日本血吸虫、广州管圆线虫及棘球蚴的血清抗体阳性率分别为16.2%(38/234)、17.8%(48/269)、11.6%(22/189)、8.8%(18/204)。结论深圳市存在华支睾吸虫、日本血吸虫、广州管圆线虫及棘球蚴病病例,应加强寄生虫病防治的宣传、监测和管理。

Objective To detect serum antibodies from suspected cases with parasitic diseases by using CDC detectionplatform and to provide technical basis for hospitals diagnosis and treatment. Methods Suspected cases of clonorchiasis,schistosomiasis, angiostrongyliasis cantonensis and eehinocoecosis from municipal hospitals and district hospitals, and fourkinds of their serum antibodies were detected by ELISA. Results The total positive rate of serum antibodies in 896suspected cases was 14.1% （126/896）. Positive rates of suspected cases from municipal hospitals and suspected cases fromdistrict hospitals were 13.6% （100/734） and 16.0% （26/162）, and the difference between the two groups in positive rates wasnot statistically significant（x2=0.646,P〉 0.05）. Positive rates of the serum antibodies against Clonorchis, Sehistosoma,Angiostrongylus and Echinococcus were 16.2% （38/234）,17.8% （48/269）, 11.6% （22/189） and 8.8% （18/204） respectively.Conclusion There were cases infected with elonorehiasis, schistosomiasis, angiostrongyliasis eantonensis and echinococeosis inShenzhen city, heath education, monitoring and management of parasitic diseases should be strengthened.