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Narcotrend指数对咪唑安定的镇静深度预测作用研究 被引量:2

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摘要 目的:评价Narcotrend用于监测咪唑安定镇静深度的准确性。方法:选择腰硬联合麻醉下行下肢手术的男性患者20例,ASAⅠ~Ⅱ级,年龄18~50岁,以血浆靶控模式输注咪唑安定,逐步升高靶控浓度至患者OAA/S镇静评分达到1分,然后降低靶控浓度直至OAA/S为4分。比较达到每个预设靶浓度时患者NT指数、效应室浓度与OAA/S的相关性,以及NT指数、效应室浓度对OAA/S、语言指令反应消失(LVC)和摇头反应消失( LSH )的预测概率。结果:诱导期 NT 指数、咪唑安定效应室浓度与 OAA/S 的相关系数分别为0.589(P <0.05)、0.647(P <0.05),苏醒期分别为0.513(P <0.05)、0.554(P <0.05)。 NT 指数、效应室浓度对OAA/S、LVC 和LSH 的预测概率均高于0.5(P <0.05)。结论:NT 指数可有效用于判断咪唑安定的镇静深度。
出处 《实用医学杂志》 CAS 北大核心 2014年第23期3725-3726,共2页 The Journal of Practical Medicine
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  • 1Somchai Amornyotin,Wichit Srikureja,Wiyada Chalayonnavin,Siriporn Kongphlay.Dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography[J].Hepatobiliary & Pancreatic Diseases International,2011,10(3):313-318. 被引量:15
  • 2张兴安,芮建中,吴群林,施冲,王若松.NONMEM法分析静滴异丙酚在中国人体的群体药代动力学[J].中国临床药理学杂志,2004,20(6):444-448. 被引量:34
  • 3于布为.理想麻醉状态与麻醉深度监测[J].现代临床医学生物工程学杂志,2006,12(4):305-307. 被引量:26
  • 4Priebe H J.The aged cardiovascular risk patient[J].Br J Anaesth,2000,85(5):763-778.
  • 5Riad W,Schreiber M,Saeed A B.Monitoring with EEC entropy decreases propofol requirement and maintains cardiovascular stability during induction of anaesthesia in elderly patients[J].Eur J Anaesthesiol,2007,24(8):684-688.
  • 6Anderson R E,Jakobsson J G.Entropy of EEG during anaesthetic induction; a comparative study with propofol or nitrous oxide as sole agent[J].Br J Anaesth,2004,92(2):167-170.
  • 7Vakkuri A,Yli-Hankala A,Sandin R,et al.Spectral entropy monitoring is associated with reduced propofol use and faster mergence in propofol-nitrous oxide-alfentanil anesthesia[J].Anesthesiology,2005,103 (2):274-279.
  • 8Ouattara A,Boccara G,Lemaire S,et al.Target-controlled infusion of propofol and remifentanil in cardiac anaesthesia:influence of age on predicted effect-site concentrations[J].Br J Anaesth,2003,90(5):617-622.
  • 9Ruhn J,Lehmann L E,R(o)pcke H,et al.Shannon entropy applied to the measurement of the electroencephalographic effects of desflurane[J].Anesthesiology,2001,95(1):30-35.
  • 10Vierti(o)ja H,Maja V,S(a)rkel(a) M,et al.Description of the entropy TM algorithm as applied in the Datex-Ohmeda S/5TM Entropy Module[J].Acta Anaesthesiol Scand,2004,48(2):154-161.

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  • 1Marcos Eduardo Lera dos Santos,Fauze Maluf-Filho,Dalton Marques Chaves,Sergio Eiji Matuguma,Edson Ide,Gustavo de Oliveira Luz,Thiago Ferreira de Souza,Fernanda C Simoes Pessorrusso,Eduardo Guimares Hourneaux de Moura,Paulo Sakai.Deep sedation during gastrointestinal endoscopy: Propofol-fentanyl and midazolam-fentanyl regimens[J].World Journal of Gastroenterology,2013,19(22):3439-3446. 被引量:17
  • 2Deutsch E,Tobias JD. Hemodynamic and respiratory changes fotlow dexmedetomine administration during general anesthesia: sevoflu- rane vs desflurane [ J ]. Paediatr Anaesth, 2007,17 ( 5 ) : 438 - 444.
  • 3Huupponen E, Maksimow A, Lapinlampi P, et al. Electroenceph- alogram spindle activity duringdexmedetomidine sedation and phys- iological sleep [ J ]. ActaAnaesthesiol Scand, 2008,52 ( 2 ) :289 - 294.
  • 4Depriest J, Gonzalez L. Comparing dexmedetomidine with midazo- lam for sedation of patients in the ICU [ J ]. JAMA, 2009,301 (23) :2439.
  • 5Kreuer S, Wilhelm W. The Narcotrend monitor[ J ]. Best Pract Res Clin Anaesthesiol, 2006, 20( 1 ) :111 - 119.
  • 6Sessler CN, Varney K. Patient-focused sedation and analgesia in the ICU [ J ]. Chest,2008,133 (2) :552 - 65.
  • 7Jiang Y, Qiao B, Wu L, et al. Application of Narcotrend monitor for evaluation of depth of anesthesia in infantsundergoing cardiac surgery: aprospective control study [ J ]. Rev Bras Anestesiol, 2013,63 (3) :273 - 278.
  • 8Kreuer S. Wilhelm W. The Narcotrend monitor[ J ]. Best Practice Research Clinical Anaesthesiology,2006,20 ( 1 ) : 111 - 119.
  • 9Panousis P. Heller AR, Burghardt M, et al. The effect of electro- myographic activity on the accuracy of the Narcotrend monitor com- pared with the Bispectral Index during combined anaesthesia [ J]. Anaesthesia,2007,62 (5) : 868 - 874.
  • 10张燕,郑利民.右美托咪啶的药理作用及临床应用进展[J].国际麻醉学与复苏杂志,2007,28(6):544-547. 被引量:224

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