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灰树花菌丝体多糖的降血脂作用 被引量:6

Hypolipidemic Role of Mycelia Polysaccharides of Grifola Frondosa
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摘要 对灰树花菌丝体进行提取纯化,得到菌丝体多糖。通过Sephadex G200柱层析图谱分析,证明灰树花菌丝体多糖为均一组分。通过小鼠降血脂实验研究,菌丝体多糖对小鼠血脂的具有明显调节作用。高血脂症模型小鼠在实验条件下给药剂量为50mg/(kg·d)时可达到治愈的程度。灰树花菌丝体多糖具有明显的降血脂作用。 Extract and purify from mycelia of grifola frondosa to obtain mycelia polysaccharide . By Sephadex G200 column chromatography map analysis ,it proved that mycelia polysaccharide of gri-fola frondosa is the homogeneous component . Through the experimental studies in mice by lowering blood fat ,mycelia polysaccharide has a significant regulatory role on mice’s blood fat .Hyperlipidemia model mice at a dose of 50 mg /(kg o d) under experimental conditions can reach the curative degree . Mycelia polysaccharides of grifola frondosa has a significant hypolipidemic role.
出处 《天津职业院校联合学报》 2014年第10期76-79,共4页 Journal of Tianjin Vocational Institutes
关键词 灰树花 菌丝体多糖 降血脂 Grifola frondosa Mycelia polysaccharide Hypolipidemic
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  • 1Kawagishi H, Nomura A, Mizuno T, et al. Isolation and characterization of a lectin from Grifola frondosa fruiting bodied[J]. Biochimica Et Biophysica Acta, 1990, 1034 : 247 - 252.
  • 2Suzuki I, Itani T, Ohno N, et al. Antitumor- activity of a polysaccharide fraction extracted from cultured fruiting bodied of Grifola frondosa[J]. Journal of Pharmacobio- dynam , 1984, 7 : 492 - 500.
  • 3Smith J E, Rowan N J, Sullivan R. Medicinal mushrooms: a rapidly developing area of biotechnology for cancer therapy and other bioactivities[J]. Biotechnology Letters, 2002, 24:1839 - 1845.
  • 4袁德云,章克昌.灰树花发酵液及其胞内纯化物的降血脂作用[J].中国药学杂志,2003,38(7):507-508. 被引量:14

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