临床药师干预对我院中药注射剂临床使用的影响

Effects of Clinical Pharmacist Intervention on Clinical Use of TCM Injections

目的:评价临床药师干预对中药注射剂临床使用的影响,为提高我院合理用药水平提供参考。方法:由临床药师对我院中药注射剂的使用进行为期1年的干预,收集干预前(2012年4-6月)、后(2013年4-6月)各1 000份住院患者的病例资料,分别设为对照组和干预组,分析两组患者使用中药注射剂的使用率、合理性、临床疗效及不良反应(ADR)的发生情况。结果:干预组的中药注射剂使用率和ADR发生率均显著低于对照组,而适应证、用法用量、溶媒的选择、溶媒用量、配伍等方面的合理性显著高于对照组,两组比较差异均有统计学意义(P<0.05)。结论:临床药师的干预可使中药注射剂的使用更为安全、合理。

OBJECTIVE： To observe the effects of clinical pharmacist intervention on the clinical use of TCM injections, and to evaluate the effect of clinical pharmacist intervention. METHODS： After one year of intervention to TCM injection, medical infor- rnation of 1 000 patients receiving TCM injections after intervention （Apr.-Jun. 2013）were collected as intervention group, while those of 1 000 patient receiving TCM injections before intervention （Apr.-Jun. 2012）were collected as control group. The utilization rate rationality, clinical efficacy and ADR of TCM injections were analyzed in 2 groups. RESULTS： The rationality of indications, usage and dosage, solvent choice, solvent amount, compatibility and other aspects were significantly improved in intervention group. Compared with control group, the clinical efficacy of intervention group was increased, and the incidence of ADR was de- creased. There was stalistical significanre between 2 groups （P（0.05）. CONCLUSIONS： The clinical pharmacist intervention makes the use of TCM iniections safer, more reasonable,and can improve the clinical efficacy.