降钙素原与C反应蛋白对细菌感染诊断价值的探讨

Diagnostic value investigation of procalcitonin and C-reactive protein for bacterial infection

目的探讨血清降钙素原(PCT)及C反应蛋白(CRP)在检测细菌感染中的价值和应用。方法随机选取142例细菌感染者及64例非细菌感染者作为研究对象,测定两组患者血中PCT和CRP的水平,分析两者用于细菌感染的价值。结果细菌感染者血清PCT与CRP水平均明显高于非细菌感染者,差异均有统计学意义(P<0.01),但PCT敏感性及特异性均优于CRP。结论血清PCT与CRP的检测对细菌性感染性疾病的早期诊断具有重要的应用价值,作为较为理想的早期检测感染性疾病的标志物,PCT检测更具有特异性。

Objective To explore the value and application of serum procalcitonin （PCT） and C-reactive protein （CRP） in the test of bacterial infection. Methods A total of 142 patients with bacterial infection and 64 patients without bacterial infection as the study objects. The levels of serum PCT and CRP in the two groups were detected for the analysis of their value for bacterial infection test. Results The levels of serum PCT and CRP in bacterial infection patients were obviously higher than those in patients without bacterial infection, and the difference had statistical significance （P〈0.01）. The sensitivity and specificity of PCT was better than those of CRP. Conclusion Detection of serum PCT and CRP has important application value for the early diagnosis of bacterial infectious diseases. PCT has great specificity as a reasonable marker for the early detection of infectious diseases.