导管介入消融治疗44例阵发性心房颤动患者临床分析

Efficacy of interventional catheter ablation in treatment of paroxysmal atrial fibrillation:a clinical analysis of 44 cases

目的探讨导管介入消融治疗阵发性心房颤动的临床效果。方法选取2013年11月至2014年5月我院收治的44例阵发性心房颤动患者,随机分成两组,每组22例,观察组采用导管介入消融治疗,对照组采用口服胺碘酮治疗,观察两组的临床治疗效果。结果经治疗,观察组的LAD明显小于对照组,治疗总有效率明显高于对照组(90.11%vs 68.18%),P<0.05,有统计学意义。结论采用导管介入消融治疗阵发性心房颤动具有显著的疗效,能够起到逆转心房重构的作用,有效维持窦性心律,促进病人尽早康复,值得临床推广。

Objective To investigate the clinical efficacy of interventional catheter ablation in the treatment of proxysmal atrial fibrillation （PAF）. Methods Fourty-four patients with PAF who were admitted to the People＆#39;s Hospital of Hunan Province from Novermber 2013 to May 2014 were randomly divided into observation group and control group. The observation group （22 cases） was given interventional ablation therapy, whereas the control group （22 cases） was provided with oral administration of amiodarone. Clincal outcomes were observed and compared between the two groups. Results The left atrial dimension in the observation group was significantly smaller than that of the control group after treatment. The overall response rate of the observation group was significantly higher than that of the control group （90.11% vs. 68.18%, P〈0.05）. Conclusion The superior efficacy of interventional catheter ablation in the management of PAF is reflected in left atrial reverse remodeling and maintenance of normal sinus rhythm, which facilitates accelerated rehibilitation of PAD patients and therefore should be promoted in clinical practice.