^(90)锶-^(90)钇敷贴联合得宝松注射治疗头面部瘢痕疙瘩的疗效观察

Application of ^(90)Sr-^(90)Y Combining Diprospan Injection in Treating Head and Face Keloids

目的观察90Sr-90Y敷贴联合得宝松注射,治疗头面部瘢痕疙瘩的临床疗效。方法 2008年1月至2013年5月,32例头面部瘢痕疙瘩患者首先于皮损内注射得宝松,每4周1次,共3~4次;待瘢痕疙瘩体积缩小、变平后,使用90Sr-90Y敷贴治疗,每次吸收剂量为400~600 cGy,每周2次,4次为一疗程,通常每个部位治疗2~3疗程,总吸收剂量小于80 Gy。结果 32例患者中治愈26例,显效4例,治愈率为81.25%,总有效率为93.75%。结论 90Sr-90Y敷贴联合得宝松注射,治疗头面部瘢痕疙瘩,方法简便、安全,疗效好,值得临床推广应用。

Objective To investigate the clinical efficacy of 90Sr-90Y application combining Diprospan injection in treating head and face keloids. Methods From Jan. 2008 to May 2013, 32 cases with head and face keloids were treated with Diprospan injection firstly, once every 4 weeks for 3-4 times. After the shrinkage and flattening of the keloids, the keloids were then treated with 90Sr-90Y （400-600 cGy）, twice a week for 2-3 periods, 4 times as one period. The total absorbed dose was less than 80 Gy. Results Among all the patients, 26 cases were healed and 4 cases were effectively treated. The cure rate was 81.25% and the effective rate was 93.75%. Conclusion Application of 90Sr-90Y combining Diprospan injection is convenient, safe and effective in treating head and face keloids, and is worthy of further application.