A型肉毒毒素改善面部动力性皱纹的近期效果观察

Short-Term Effect Observation of Botulinum Toxin Type A for the Treatment of Hyperkinetic Line of the Face

目的 探讨应用A型肉毒毒素治疗面部动力性皱纹的特点及效果评价.方法 2012年11月至2013年6月,78例面部皱纹患者,均为女性,年龄27～46岁,应用A型肉毒毒素进行面部除皱,包括额纹48例,鱼尾纹30例.注射前及注射后1、3、6、9个月分别照相,比较面部皱纹变化情况,结合患者自我感觉等指标,综合分析A型肉毒毒素注射除皱的近期效果.结果 所有78例患者术后随访9个月,医患双方就术后效果共同进行评价,注射部位皱纹消除明显,患者对治疗效果满意.结论 应用A型肉毒毒素治疗面部动力性皱纹,疗效良好,安全方便,副作用少,术后满意度高.

Objective To determine the efficacy of Botulinum toxin type A （BTA） for the treatment of hyperkinetic lines of the face. Methods A total of 78 patients who received BTA injection to remove facial wrinkles from December 2012 to June 2013 were enrolled. All of 78 patients were females and the age of the patients ranged from 27 to 46 years. The treatment was done in two different sessions and divided into 2 treatment subgroups of forehead （48）, crow＇s feet （30）. The short-term efficacy of BTA was analyzed at the injection day and 1 month, 3 months, 6 months and 9 months after injection. Efficacy was evaluated by contrast of photo difference, measuring changes of facial wrinkles and patient self-evaluation between pre-operation and post- operation. Results All the patients were followed up for a period of 9 months and graded for the response to treatment with BTA by the operator, observer and the patient independently using the facial wrinkle scale （FWS）. These cases who received BTA injection had significant improvement in the skin around the eye status and forehead,The results of applying BTA for the treatment of hyperkinetic lines of the face were satisfactory. Conclusion BTA is characterized with a high successful rate and rare complication. It is an ideal method for the treatment of hyperkinetic lines of the face.