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羟考酮临床治疗研究进展 被引量：42

Development of Oxycodone in Clinical Treatment
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摘要 羟考酮(oxycodone)是由蒂巴因(thebaine)改造合成的阿片类中枢神经镇痛药。近几年,随着新的羟考酮剂型的开发,该药物在急性疼痛以及慢性疼痛的控制中均广泛使用,并且出现与少量阿片类药物拮抗剂联用镇痛的方式。本文综述羟考酮的基本药理学性质以及临床应用进展。 Oxycodone is a central nervous system opioid analgesics reformed from thebaine. In recent years, with the development of the formulation of oxycodone, it has been an effective treatment for acute pain and chronic pain. In addition, oxycodone plus opioid receptor antagonist has been developed to improve analgesia in clinical. This article reviews the basic pharmacological properties of oxycodone and its clinical treatment development.
作者 张杜枭 葛卫红 于锋 谢菡
机构地区 南京大学医学院附属鼓楼医院药学部 中国药科大学临床药学教研室
出处 《药学与临床研究》 2014年第6期527-531,共5页 Pharmaceutical and Clinical Research
关键词 羟考酮 药理学 临床应用 急性疼痛 慢性疼痛 药物联用 Oxycodone Pharmacology Clinical treatment Acute pain Chronic pain Drug combination
分类号 R971.1 [医药卫生—药品]
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参考文献41

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二级参考文献16

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共引文献31

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引证文献42

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药学与临床研究
2014年 第6期

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