蓝莓红景天胶囊制备及抗运动疲劳活性研究

Study on Preparation of Blueberries Rhodiola rosea Capsule and Its Anti-fatigue Activity on Sports

以蓝莓和红景天为原料,研究蓝莓红景天胶囊的制备工艺及其抗运动疲劳活性。研究结果表明:蓝莓红景天胶囊的制备工艺为:蓝莓红景天提取物、乳糖和微晶纤维素质量比为15︰7︰7,5% PVP的40%乙醇溶液作黏合剂,黏合剂添加量为70%,此条件提高颗粒流动性和改善颗粒吸湿性,提高合格率。通过测定小鼠力竭运动后肝糖原、肌糖原含量和血清尿素氮、血红蛋白含量,研究蓝莓红景天胶囊对抗运动疲劳活性。结果表明,蓝莓红景天胶囊能提高肝糖原和肌糖原的含量,降低血尿素氮含量,提高血红蛋白的浓度。蓝莓红景天胶囊具有较好的抗运动疲劳活性。

Using blueberries and Rhodiola rosea as row material, this study mainly discussed the preparation technology of blueberries Rhodiola rosea capsule and its anti-fatigue activity on sports. The optimum preparation conditions of blueberries Rhodiola rosea capsule were determined, such as mass ratio of blueberries Rhodiola rosea extraction, lactose and microcrystalline cellulose for 15︰7︰7, 5% PVP soluble in 40% ethanol solution as adhesive, and the added proportion of adhesive for 70%. The liquidity and hygroscopic property of particles was improved, and qualified rate of particles was also improved. The influence of anti-fatigue activity on sports of blueberries Rhodiola rosea capsule was tested by the content of glycogen and muscle glycogen, and also was tested by the content of blood urea nitrogen and hemoglobin of mice. It shows that the content of liver glycogen and muscle glycogen of mice were increased, the content of blood urea nitrogen of mice was decreased, and the concentration of hemoglobin concentration of mice was improved. So blueberries Rhodiola rosea capsule has a good anti-fatigue activity on sports.