地佐辛联合丙泊酚用于输卵管结扎术镇痛效果的观察

Study on anesthetic effect of dezocine combined with propofol in oviduct ligation

目的:探讨地佐辛联合丙泊酚用于输卵管结扎术的镇痛效果。方法:将受术者随机分为两组,每组100例。A组用1%利多卡因局部麻醉;B组除用1%利多卡因局部麻醉外,术前15min静脉注射地佐辛5mg,进腹探查前加深麻醉,静注丙泊酚2mg/kg。观察记录不同时间点(麻醉前、切皮、提取输卵管和抽芯包埋法结扎输卵管、术毕和术后)的收缩压(SBP)、舒张压(DBP)、血氧饱和度(SPO2)、心率(HR)、心电图,以及手术时间、提取输卵管次数。结果:B组的SBP、DBP、SPO2、HR在不同时间点均表现平稳;A组在处理输卵管时波动较大,两组差异有统计学意义(P<0.05)。手术时间及提取输卵管次数B组均少于A组,差异有统计学意义(P<0.01)。结论:地佐辛联合丙泊酚用于输卵管结扎术镇痛较完善,血流动力学稳定,且缩短了手术时间,值得临床应用。

Objective： To explore the anesthetic effect of dezocine combined with propofol in oviduct ligation. Methods： Two hundred patients were randomly divided into two groups. Women in group A （n= 100） was treated with 1 % lidocaine local anesthesia injections, and those in group B （n= 100） was treated with 5 mg of dezocine combined with 2 mg/kg of propofol besides 1% lidocaine local anesthesia injection. Systolic pressure （SBP）, diastolic pressure（DBP）, oxygen saturation （SPO2）, heart rate （HR）, electrocardiograms and the duration of operation as well as the number of pulling fallopian tube at different points in time were evaluated. Results： Compared with group A, SBP, DBP, SPO2, HR at different points in time showed more stable in Group B （P〈0.05）, and shorter operation time and fewer pulling were found in Group B （P〈0.01）. Conclusion： The use of dezocine combined with propofol in oviduct ligation is safe and efficient, and can be applied in clinical practice.