期刊文献+

甲状腺转录因子l在肺癌诊断与鉴别诊断中的应用及意义 被引量:1

下载PDF
导出
摘要 根据WHO的统计,近十多年来,全球的癌症死亡率不断上升,其中以肺癌的死亡率增长最快[1]。在我国,其发病率已由原恶性肿瘤的第6位跃居为第2位,在城市中死亡率占第1位‘引。由于绝大多数肺癌临床确诊时已是中晚期,因此肺癌的早期诊断是决定患者预后的关键因素。甲状腺转录因子1(TTF-1)是近年来发现的一个新的肿瘤标志物。在肺癌特别是腺癌的表达具有高度敏感性和特异性。
出处 《检验医学与临床》 CAS 2014年第A02期309-312,共4页 Laboratory Medicine and Clinic
  • 相关文献

参考文献20

  • 1BachPB.Smokingasafactorincausinglungcancer[J].JAMA,2009,301(5):539-541.
  • 2钟殿胜,陈宝元.早期肺癌诊断的进展[J].临床内科杂志,2010,27(4):224-226. 被引量:4
  • 3KhoorA,Stahlman MT,GrayME,etal.TemporalspatialdistributionofSP-BandSP-CproteinsandmRNAsinde-velopingrespiratoryepi-theliumofhumanlung[J].JHis-tochem Cytoehem,l994,42(17):1187-1199.
  • 4陆鸣,董亚文,王翠芝,陈书媛,韦萍,刘金香.TTF-1在肺腺癌中的表达特点及意义[J].诊断病理学杂志,2007,14(5):353-356. 被引量:5
  • 5韩高华,周晓军,孟奎,陆珍凤.TTF-1在肺腺癌中的表达及其诊断意义[J].临床与实验病理学杂志,2002,18(6):595-597. 被引量:21
  • 6LoretoCD,LauroVD,PuglisiF,etal.Immunocytochemi-calex-pressionoftissuespecifictranscriptionfactor-1inlungcarcinoma[J].JClinPathol,1997,50(15):30-32.
  • 7刘建,覃丹,颜桂芳.P63和TTF-1在肺癌组织中的表达及意义[J].中国组织化学与细胞化学杂志,2008,17(3):289-292. 被引量:6
  • 8ChangYL,LeeYC,LiaoWY,etal.Theutilityandlimita-tionofthyroidtranscriptionfactor-1proteininprimaryand metastaticpulmonaryneoplasms[J].Lung Cancer,2004,4(2):149-157.
  • 9BejaranoPA,BaughmanRP,BiddingerPW,etal.Surfaet-antproteinsandthyroidtranscriptkmfactor-1inpulmo-naryandbreastcarcino-mas[J].ModPathol,1996,9(4):445-452.
  • 10AgoffSN,LampsLW,Philip AT,etal.Thyroidtran-scriptionfactor-1isexpressedinextrapulmonarysmacellcarcinomasbutnotinotherextrapulmonaryneuroen-doerinetumors[J].ModPathol,2000,13(3):238-242.

二级参考文献45

  • 1王红梅,周小鸽.TTF-1在肺癌诊断及鉴别诊断中的应用价值[J].诊断病理学杂志,2005,12(6):441-443. 被引量:34
  • 2李连弟,鲁凤珠,张思维,牧人,孙秀娣,皇甫小梅,孙杰,周有尚,欧阳宁慧,饶克勤,陈育德,孙爱明,薛志福,夏毅.中国恶性肿瘤死亡率20年变化趋势和近期预测分析[J].中华肿瘤杂志,1997,19(1):3-9. 被引量:869
  • 3Travis WD, Colby TV, Corrin B et al. (WHO) Histological typing of lung and pleural tumors. 3rd ed, Berlin:Springer, 1999:35
  • 4Di Loreto C, Di Lanro V,Puglisi F et al. Immunohistological expression of tissue special transcription factor-1 in lung carcinoma. J Clin Pathol,1997;50(1):30~2
  • 5Hecht JL,Pinkus JL,Weinstein LJ et al. The value of TTF-1 in cytologic preparation as a marker for metastatic adenocarcinoma of lung origin. Am J Clin Pathol, 2001;116(4):483~8
  • 6Kaufmann O, Dietel M. Thyroid transcription factor-1 is the superior immunohistochemical marker for pulmonary adenocarcinomas and large cell carcinomas compared to surfactant proteins A and B. Histopathology, 2000;36:8~16
  • 7Reis-Filho JS, Carrilho C,Valenti C et al. Is TTF-1 a good immunohistochemical marker to distinguish primary from metastatic lung adenocarcinomas? Pathol Res Pract, 2000;196(12):835~40
  • 8Ikeda K, Clark JC,Shaw-white JR et al. Gene structrue and expression of human thyroid transcription factor-1 in respiratory epithelia cells. J Biol Chem, 1995;270:8108~14
  • 9Moran CA, Suster S. Tumors of the Lung and Pleura. In: Fletcher CDM ed. Diagnostic Histopatholgy of Tumors. 2nd ed, London: Churchill, Livingstone,2000:171~208
  • 10Fetsch PA, Simsir A, Brosky K, et al. Comparison of three commonly used cytologic preparations in effusion immunocytochemistry. Diagn Cytopathol, 2002,26 (1):61~6.

共引文献37

同被引文献6

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部