2-(1E,3E)-5-氧代-5-(4-(2-吡啶)哌嗪)-1,3-戊二烯苯甲氰的合成及生物活性

Synthesis and Biological Activity of 2-((1E,3E)-5-Oxo-5-(4-(pyridin-2-yl) piperazin-1-yl) penta-1,3-dienyl)benzonitrile

以2-溴苯氰为起始原料经5步合成标题化合物,并测试其生物活性,产物结构经1HNMR、13CNMR和MS表征。

A compound,2-（（ 1E,3E）-5-oxo-5-（ 4-（ pyridin-2-yl） piperazin-1-yl） penta-1,3-dienyl） benzonitrile,was synthesized from bromo benzonitrile by a five-step reaction. The structures were confirmed by ^1HNMR,^13CNMR and MS. And the bioactivity was invesitigated.