连续性护理干预对胃癌术后患者围化疗期不良反应和生活质量的影响

Effect of continuous nursing intervention on postoperative gastric cancer patients with chemotherapy adverse reaction and quality of life

目的：探讨连续性护理干预对胃癌术后患者围化疗期不良反应和生活质量的影响。方法选取住院治疗的胃癌、术后需要化疗的患者152例，随机分为对照组和干预组，每组76例。对照组患者给予常规护理，干预组患者在此基础上给予连续性护理干预。采用问卷调查的方法分别收集患者治疗1-3个疗程后的生活质量情况，随访两组患者三个疗程中不良反应发生情况。结果干预组患者常见不良反应发生率均低于对照组（均P＜0.05），肝肾功能异常发生率两组间无统计学差异。干预1个疗程和2个疗程后干预组患者生活质量改善均优于对照组（均P＜0.05），干预3个疗程之后干预组患者生活质量显著优于对照组（ P＜0.01）。结论连续性护理干预可以有效降低化胃癌术后化疗不良反应发生率，提高患者的生活质量。

Objective To investigate the effect of continuous nursing intervention on postoperative gastric cancer patients with chemotherapy adverse reaction and quality of life.Methods A total of 152 gastric cancer patients treated with postoperative chemotherapy were randomly divided into control group and intervention group.The control group was given conventional nursing, patients in the intervention group were added continuous nursing intervention.The questionnaire survey was used to assess quality of life after 1-3 treatment.The adverse reactions and quality of life were compared between the two groups.Results The incidence of adverse reaction of intervention group was lower than that of control group, the incidence of liver and kidney functions had no significant defference between the two groups.The quality of life of intervention group was better than that of control group after 1-2 courses of treatment （ P〈0.05） and 3 courses of treatment （ P〈0.01） .Conclusions The continuous nursing intervention can effectively reduce incidence of adverse reaction of chemotherapy, im-prove the quality of life of postoperative gastric cancer patients.