仿生涂层控制Mg-Zn-Sr合金的降解速率

Controlling the Biodegradation Rate of Mg-Zn-Sr Alloy Using Biomimetic Coating

镁合金作为生物医用材料面临最大的问题是降解速率过快,不能与骨愈合的速率配合.通过仿生法在Mg-Zn-Sr合金表面形成涂层,利用X射线衍射和扫描电子显微镜对涂层结构和形貌进行分析与观察;采用电化学和浸泡腐蚀实验,研究涂层对Mg-Zn-Sr合金在人体模拟液中降解速率的影响.实验结果表明:仿生法在合金表面形成的涂层为羟基磷灰石涂层;羟基磷灰石涂层提高了Mg-Zn-Sr合金在人体模拟溶液中的耐腐蚀性能.

Magnesium alloy has attracted the attention of the biomaterials community as a potential biodegradable metallic candidate for stents and orthopedic applications. The high corrosion rate of magnesium alloy confines their application in clinical. Therefore, it＇s one of the main approaches to develop Mg-based biomaterials with good corrosion resistance and high strength for biomedical engineering. The apatite coatings were deposited on matrix through biomimetic method. The coating was characterized by XRD and SEM. The degradation rates of the samples without and with hydroxyaptite coating were researched in the simulated body fluid （SBF）. The results showed that surface modification improves the corrosion resistance. The degradation rate of the Mg-Zn-Sr alloy with coating was slower than that of the alloy without coating on the surface.