多环黏膜套扎切除术治疗食管胃交界部早癌及癌前病变的初步评价

Multiband mucosectomy in treatment of early cancer and precancerous lesions of esophagogastric junction

回顾性分析2013年1月至2014年2月在扬州市第一人民医院接受多环黏膜套扎切除术（MBM）治疗的18例食管胃交界部（EGJ）早癌及癌前病变患者的临床资料,总结治疗效果及术后并发症发生情况.结果显示,18例患者均顺利完成手术,平均手术操作时间35.8 min.3例术中出血,内镜下成功止血;1例术中发生微小穿孔,以金属夹夹闭痊愈.术后病理诊断：5例为黏膜内癌,8例为高级别上皮内瘤变,5例为低级别上皮内瘤变.随访期间未见复发病例.提示,MBM可有效治疗EGJ早癌及癌前病变,具有安全、操作简便的优点.

Eighteen patients with early cancer and precancerous lesions of esophagogastric junction underwent muhiband mucosectomy （MBM） in Yangzhou First People＇s Hospital from January 2013 to February 2014. The clinicopathological data of patients were analyzed retrospectively and the short-term efficacy and safety of MBM were evaluated. Operations were successful in all 18 cases. The mean operative time was 35.8 min. Intraoperative bleeding occurred in 3 cases and successfully managed by endoscopic hemostasis. Small perforation occurred in 1 patient and was closed by metal clips. Pathological examination showed mucosal cancer in 5 cases, high-grade intraepithelial neoplasia in g cases and low-grade intraepithelial neoplasia in 5 cases. No relapse of cancer was found during follow-up. Results indicate that MBM is an effective and safe method in treatment of early cancer and precancerous lesions in the esophagogastric junction.