145例中成药不良反应报告分析

Report of 145 Cases of Adverse Drug Reactions of Traditional Chinese Patent Medicines

目的为中成药的临床合理应用提供参考。方法对医院2009年至2013年收集的145例中成药不良反应报告进行统计和分析。结果 145例中成药不良反应中,52例60岁以上患者,占35.86%;给药途径以静脉滴注为主,共120例,占82.76%;不良反应累及器官或系统最多的是皮肤及其附件,共77例,占53.10%。结论加强中成药不良反应监测,促进其合理使用,以减少和避免不良反应发生。

Objective To provide reference for rational use of traditional Chinese patent medicines in clinic. Methods 145 cases of adverse drug reactions（ADR） reports collected in our hospital during January 2009 to December 2013 were performed the statistical analysis. Results Among 145 cases of ADR,52 cases were over 60 years old and accounted for 36. 86%; the administration route was dominated by the intravenous drip,which were 120 cases and accounted for 82. 76%; the most commonly affected organs or systems were skin and its appendages,which accounted for 48. 43%（77 cases）. Conclusion Strengthening the monitoring of ADR of traditional Chinese patent medicines and promoting their clinical rational use can reduce or avoid the occurrence of ADR.