蒙特利尔认知评估量表在高血压脑出血患者认知功能筛查中的应用

Montreal cognitive assessment scales applied in screening for cognitive function in patients with hypertensive cerebral hemorrhage

目的探讨蒙特利尔认知评估量表(Mo CA)对高血压脑出血患者认知功能损害评估的意义。方法选择76例高血压脑出血患者,在其发病后6个月至2年内再次就诊,应用Mo CA及简易精神状态量表(MMSE)检测其认知功能。首先用MMSE进行认知评测,根据患者教育程度对应的MMSE临界值筛选出评分在正常参考范围的高血压脑出血患者;对这些高血压脑出血患者继续应用Mo CA量表评测,并以Mo CA量表评分26分为临界值将受试者进行分组比较。结果经MMSE量表评测正常的高血压脑出血患者76例,MMSE评分为(27.5±2.3)分,Mo CA评分(23.2±4.2)分,其中Mo CA评测正常(≥26分)19例(25%),评测异常(<26分)57例(75%),Mo CA评测异常组在视空间与执行能力、命名、注意、语言、抽象、延迟记忆、定向力等认知领域得分低,差异均有统计学意义(P<0.01)。结论 Mo CA量表测试可以反映高血压脑出血患者认知功能损害的临床特征,可作为高血压脑出血患者认知功能受损筛查的良好工具,其应用价值优于MMSE。

Objective To investigate the significance of Mo CA in the evaluation of the damage of cognitive function in patients with hypertension cerebral hemorrhage. Methods A total of 76 patients with hypertension cerebral hemorrhage who visited the doctor again after the onset of 6 months to 2 years were selected,and the cognitive function were detected by Mo CA and MMSE. First of all,used the MMSE to evaluate the cognitive function according to the patient education degree corresponding with the critical value of MMSE,selected the hypertension cerebral hemorrhage patients with normal value. For these hypertension cerebral hemorrhage patients,continue to test the cognitive function application of Mo CA,and with Mo CA rating scale,divided them into different groups and compared. Results There were 76 cases with normal value of MMSE,and the MMSE score was（ 27. 5 ± 2. 3） points,Mo CA score（ 23. 2 ± 4. 2） points,including 19 patients（ 25%） with normal Mo CA（ ≥26）,57 cases（ 75%） with anomaly Mo CA（〈26）,the anomaly Mo CA group had lower scales in visual space and executive ability,naming,note,language,abstract and delayed memory,directional force and cognitive domain score,the differences were statistically significant（ P〈0. 01）. Conclusion Mo CA scale test can reflect the damage clinical characteristics of cognitive function in patients with hypertension cerebral hemorrhage. It can be used as a good screening tool for the damage of cognitive function in patients with hypertension cerebral hemorrhage,and its application value is better higher MMSE.