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银杏叶对新生鼠缺氧缺血性脑损伤后Nestin蛋白表达的影响 被引量：4

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摘要 目的:研究银杏叶提取物(Gb E)对新生大鼠缺氧缺血性脑损伤(HIBD)后Nestin蛋白表达的影响。方法:72只7 d龄SD大鼠制备HIBD模型,随机分为Gb E治疗组、生理盐水(NS)治疗组和假手术组,应用免疫组化的方法观察Gb E对脑组织Nestin表达的影响。结果:脑组织Nestin的表达在NS治疗和Gb E治疗3 d开始增高,7 d达到最高峰,Gb E治疗组与假手术组和NS治疗组比较有显著性差异(P<0.05)。结论:Gb E可提高HIBD大鼠脑组织Nestin的表达,具有诱导神经干细胞增殖的作用。
作者 宋文秀 卢飞艳 王艳萍 吴晓媚
机构地区 广东省珠海市遵义医学院第五附属医院儿科
出处 《中国中医基础医学杂志》 CAS CSCD 北大核心 2014年第12期1635-1636,共2页 JOURNAL OF BASIC CHINESE MEDICINE
关键词 银杏叶提取物 NESTIN 缺氧缺血性脑损伤 HIBD
分类号 R285.5 [医药卫生—中药学]
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参考文献8

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二级参考文献10

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中国中医基础医学杂志
2014年 第12期

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