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右美托咪啶对脑外伤患者围手术期脑氧代谢的影响 被引量:5

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摘要 目的研究右美托咪定对脑外伤患者围手术期脑氧代谢的影响。方法脑损伤手术患者63例,按年龄分为0-12岁(A组,15例)、13-17岁(B组,18例)和18-80岁(C组,30例),麻醉前静注右美托咪定0.5μg/kg。比较切皮前、手术1、2h和缝合切口时的动脉-颈内静脉球部血氧差(Da-jvO2)和脑氧摄取率(ERO2)。结果三组术中ERO2和Da-jvO2均较切皮前提高(P<0.05),B、C组高于A组(P<0.05)。经治疗后,A组患者缺氧症状缓解或解除所用时间为(4.3±0.8)min,少于B组的(7.2±0.7)min和C组的(10.2±0.5)min(P<0.05),C组长于B组(P<0.05)。结论右美托咪啶对不同年龄层次的脑外伤患者均有改善脑氧代谢的作用。
出处 《江苏医药》 CAS 北大核心 2014年第23期2910-2911,共2页 Jiangsu Medical Journal
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