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早产儿产房复苏用氧的相关问题 被引量:5

Issues Related to Oxygen Used in the Resuscitation of Preterm Infants in Delivery Room
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摘要 在我国,新生儿尤其是早产儿窒息发生率较高。近年高氧血症对新生儿的危害越来越受到重视,产房复苏中如何合理用氧的观点亦发生了巨大改变。目前多数研究资料及相关指南仅局限于足月儿产房复苏中如何合理用氧,将足月儿研究的结论应用于早产儿并不适合。早产儿产房复苏技术的进一步完善,对提高窒息早产儿存活率和减少神经系统后遗症有极大帮助。将早产儿窒息复苏用氧治疗中新的研究成果进行及时推广和应用,具有重要的临床价值和社会意义。 There is high incidence of neonatal asphyxia in China, especially among preterm infants. The harm of hyperoxia on neonates has been more and more focused in recent years, aeeompaning with great ehanges on how to use oxygen reasonably in delivery room. Most research data and related guidelines were limited to full-term infants, which were not suitable for preterm infants. More and more preterm infants will survive without serious neurological sequelae with further improvement on resuscitation of in the delivery room. Appropriate promotion and application of new perspectives in resuscitation of preterm infants has important clinical values and social significance.
出处 《中华妇幼临床医学杂志(电子版)》 CAS 2014年第6期100-103,共4页 Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金 国家自然科学基金资助项目(81100457) 四川省科技厅基金资助项目(2013SZ0031) 国家临床重点专科(儿科新生儿专业)建议项目基金资助项目(1311200003303)~~
关键词 婴儿 早产 窒息 复苏术 支气管肺发育不良 Infant, premature Asphyxia Resuscitation Oxygen Bronchopulmonary dysplasia
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参考文献29

  • 1Lawn JE, Blencowe H, Oza S, et al. Every Newborn: progress, priorities, and potential beyond survival[J]. Lancet, 2014, 384 (9938) : 189-205.
  • 2Moore T, Hennessy EM, Myles J, et al. Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies[J]. BMJ, 2012, 345:e7961.
  • 3Chessex P, Watson C, Kaczala GW, et al. Determinants of oxidant stress in extremely low birth weight premature infants[J]. Free Radic Biol Med, 2010, 49(9) :1380-1386.
  • 4Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production [J]. Pediatr Res,1088,23(2) :143-150.
  • 5Georgeson GD, Szony BJ, Streitman K, et al. Antioxidantenzyme activities aredecreased in preterm infants and in neonates born via caesarean section[J]. Eur JObstet Gynecol Reprod Biol, 2002, 103(2): 136-139.
  • 6Mocatta TJ, Winterbourn CC, Inder TE, et al. The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma[J]. Free Radic Res , 2004, 38(2):185-191.
  • 7Davis JM, Auten RL. Maturation of the antioxidant system and the effects on preterm birth[J]. Semin Fetal Neonatal Med, 2010, 15(4) :191-195.
  • 8Nassi N, Ponziani V, Becatti M, et al. Anti-oxidant enzymes and related elements in term and preterm newborns[J]. Pediatr Int, 2009, 51(2) :183-187.
  • 9Asikainen TM, Heikkila P, Kaarteenaho-Wiik R, et al. Cellspecific expression of manganese superoxide dismutase protein in the lungs of patients with respiratory distress syndrome, chronic lung disease, or persistent pulmonary hypertension [J]. Pediatr Pulmonol, 2001, 32(3): 193-200.
  • 10Gien J, Kinsella JP. Pathogenesis and treatment of bronchopulmonary dysplasia[J]. Curr Opin Pediat, 2011, 23(3) : 305-313.

二级参考文献29

  • 1Lawn JE, Blencowe H, Oza S, et al. Every Newborn: progress, priorities, and potential beyond survival[J]. Lancet, 2014, 384 (9938) : 189-205.
  • 2Moore T, Hennessy EM, Myles J, et al. Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies[J]. BMJ, 2012, 345:e7961.
  • 3Chessex P, Watson C, Kaczala GW, et al. Determinants of oxidant stress in extremely low birth weight premature infants[J]. Free Radic Biol Med, 2010, 49(9) :1380-1386.
  • 4Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production [J]. Pediatr Res,1088,23(2) :143-150.
  • 5Georgeson GD, Szony BJ, Streitman K, et al. Antioxidantenzyme activities aredecreased in preterm infants and in neonates born via caesarean section[J]. Eur JObstet Gynecol Reprod Biol, 2002, 103(2): 136-139.
  • 6Mocatta TJ, Winterbourn CC, Inder TE, et al. The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma[J]. Free Radic Res , 2004, 38(2):185-191.
  • 7Davis JM, Auten RL. Maturation of the antioxidant system and the effects on preterm birth[J]. Semin Fetal Neonatal Med, 2010, 15(4) :191-195.
  • 8Nassi N, Ponziani V, Becatti M, et al. Anti-oxidant enzymes and related elements in term and preterm newborns[J]. Pediatr Int, 2009, 51(2) :183-187.
  • 9Asikainen TM, Heikkila P, Kaarteenaho-Wiik R, et al. Cellspecific expression of manganese superoxide dismutase protein in the lungs of patients with respiratory distress syndrome, chronic lung disease, or persistent pulmonary hypertension [J]. Pediatr Pulmonol, 2001, 32(3): 193-200.
  • 10Gien J, Kinsella JP. Pathogenesis and treatment of bronchopulmonary dysplasia[J]. Curr Opin Pediat, 2011, 23(3) : 305-313.

共引文献15

同被引文献63

  • 1早产儿治疗用氧和视网膜病变防治指南[J].中华医学杂志,2005,85(10):661-662. 被引量:27
  • 2Lawn JE, Blencowe H, Oza S, et al. Every Newborn: progress, priorities, and potential beyond survival[J]. Lancet, 2014, 384 (9938) : 189-205.
  • 3Moore T, Hennessy EM, Myles J, et al. Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies[J]. BMJ, 2012, 345:e7961.
  • 4Chessex P, Watson C, Kaczala GW, et al. Determinants of oxidant stress in extremely low birth weight premature infants[J]. Free Radic Biol Med, 2010, 49(9) :1380-1386.
  • 5Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production [J]. Pediatr Res,1088,23(2) :143-150.
  • 6Georgeson GD, Szony BJ, Streitman K, et al. Antioxidantenzyme activities aredecreased in preterm infants and in neonates born via caesarean section[J]. Eur JObstet Gynecol Reprod Biol, 2002, 103(2): 136-139.
  • 7Mocatta TJ, Winterbourn CC, Inder TE, et al. The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma[J]. Free Radic Res , 2004, 38(2):185-191.
  • 8Davis JM, Auten RL. Maturation of the antioxidant system and the effects on preterm birth[J]. Semin Fetal Neonatal Med, 2010, 15(4) :191-195.
  • 9Nassi N, Ponziani V, Becatti M, et al. Anti-oxidant enzymes and related elements in term and preterm newborns[J]. Pediatr Int, 2009, 51(2) :183-187.
  • 10Asikainen TM, Heikkila P, Kaarteenaho-Wiik R, et al. Cellspecific expression of manganese superoxide dismutase protein in the lungs of patients with respiratory distress syndrome, chronic lung disease, or persistent pulmonary hypertension [J]. Pediatr Pulmonol, 2001, 32(3): 193-200.

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