水生生态系统中POPs的免疫毒理学研究进展

Current progress on immunotoxicity of POPs in the aquatic ecosystem

持久性有机污染物(POPs)不仅具有"三致"效应(致癌、致畸、致突变)和遗传毒性,而且对内分泌系统、神经系统、免疫系统等具有毒害作用。再加上自身具有难降解、易蓄积、可长距离运输等特点,给水生生态系统以及人类带来极大危害。结合当前的研究趋势,围绕水生生物中持久性有机污染物的免疫毒性进行了介绍,同时回顾了近年来该类污染物的污染状况及各方面毒性效应,并对目前该领域中存在的问题及下一步需要关注的热点进行了讨论和总结。

POPs have been identified not only carcinogenic,mutagenic,teratogenic and genotoxic,but also toxic to endocrine system,nervous system and immune system etc. In addition,POPs also have been observed to persist,bioaccumulate and be capable of large transportation in the environment,and done a lot of harm to aquatic ecosystem or human. In this paper,the study of immunotoxicity of POPs in aquatic organisms was introduced in details. In addition,a review of pollution and toxicity in many respects of POPs was stated,and existing problems and the focus of development in this field were pointed out.